Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS-Reference-Cited by-同舟云学术

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Published:2014-09 Issue:5 Volume:83 Page:1043-1050
ISSN:0896-6273
Container-title:Neuron
language:en
Short-container-title:Neuron

Author:

Su Zhaoming,Zhang Yongjie,Gendron Tania F.,Bauer Peter O.,Chew Jeannie,Yang Wang-Yong,Fostvedt Erik,Jansen-West Karen,Belzil Veronique V.,Desaro Pamela,Johnston Amelia,Overstreet Karen,Oh Seok-Yoon,Todd Peter K.,Berry James D.,Cudkowicz Merit E.,Boeve Bradley F.,Dickson Dennis,Floeter Mary Kay,Traynor Bryan J.,Morelli Claudia,Ratti Antonia,Silani Vincenzo,Rademakers Rosa,Brown Robert H.,Rothstein Jeffrey D.,Boylan Kevin B.,Petrucelli Leonard,Disney Matthew D.

Publisher

Elsevier BV

Subject

General Neuroscience

Reference23 articles.

1. Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS;Ash;Neuron,2013

2. An RNA hairpin to G-quadruplex conformational transition;Bugaut;J. Am. Chem. Soc.,2012

3. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS;DeJesus-Hernandez;Neuron,2011

4. A small molecule that targets r(CGG)(exp) and improves defects in fragile X-associated tremor ataxia syndrome;Disney;ACS Chem. Biol.,2012

5. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention;Donnelly;Neuron,2013

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