Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy

Author:

Nakamae S.,Kobatake Y.,Suzuki R.,Tsukui T.,Kato S.,Yamato O.,Sakai H.,Urushitani M.,Maeda S.,Kamishina H.

Funder

Ministry of Education, Culture, Sports, Science and Technology of Japan

Ministry of Health, Labour and Welfare of Japan

Publisher

Elsevier BV

Subject

General Neuroscience

Reference34 articles.

1. Comparison of immunoreactivities in 4-HNE and superoxide dismutases in the cervical and the lumbar spinal cord between adult and aged dogs;Ahn;Exp Gerontol,2011

2. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death;Arrasate;Nature,2004

3. Degenerative myelopathy in the aging German Shepherd dog: clinical and pathologic findings;Averill;J Am Vet Med Assoc,1973

4. Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis;Awano;Proc Natl Acad Sci USA,2009

5. Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis;Basso;J Biol Chem,2013

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