TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons
Author:
Funder
JSPS KAKENHI
Intramural Research Grant
Alzheimer’s and Aging Research Center
Torrey Pines Institute for Molecular Studies
Publisher
Elsevier BV
Subject
General Neuroscience
Reference52 articles.
1. IGF-1 promotes beta-amyloid production by a secretase-independent mechanism;Araki;Biochem Biophys Res Commun,2009
2. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia;Bao;Protein Cell,2016
3. Macroautophagy is not directly involved in the metabolism of amyloid precursor protein;Boland;J Biol Chem,2010
4. Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy;Bordi;Autophagy,2016
5. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination;Brewer;J Neurosci Res,1993
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Integrative analysis reveals key lysosomal genes as potential therapeutic targets in Alzheimer’s disease;Metabolic Brain Disease;2024-08-16
2. An Epigenetic Manifestation of Alzheimer's Disease: DNA Methylation;Actas Españolas de Psiquiatría;2024-06-05
3. Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer’s disease;Alzheimer's Research & Therapy;2024-06-03
4. Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease;Journal of Neuroinflammation;2023-10-20
5. Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation;Neuron;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3