Family history of aortic disease predicts disease patterns and progression and is a significant influence on management strategies for patients and their relatives

Author:

Brown Chase R.,Greenberg Roy K.,Wong Shen,Eagleton Matthew,Mastracci Tara,Hernandez Adrian V.,Rigelsky Christina M.,Moran Rocio

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Surgery

Reference26 articles.

1. National Vital Statistics Reports. Available at: http://www.cdc.gov/nchs/data/nvsr/nvsr59/nvsr59_10.pdf Accessed January 23, 2012.

2. Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections;Guo;Nat Genet,2007

3. TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections;Inamoto;Cardiovasc Res,2010

4. Exome sequencing identifies SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms;Regalado;Circ Res,2011

5. The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients;McColgan;Int Surg,2009

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