A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-κB and the PKCα/PI3-K/Akt pathways-Reference-Cited by-同舟云学术

A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-κB and the PKCα/PI3-K/Akt pathways

Published:2014-12 Issue: Volume:78 Page:76-85
ISSN:0197-0186
Container-title:Neurochemistry International
language:en
Short-container-title:Neurochemistry International

Author:

Xu Da-Ping,Zhang Kun,Zhang Zai-Jun,Sun Ye-Wei,Guo Bao-Jian,Wang Yu-Qiang,Hoi Pui-Man,Han Yi-Fan,Lee Simon Ming-Yuen

Funder

Science and Technology Development Fund

Research Committee of the University of Macau

2012 Hong Kong Scholars Program

China Postdoctoral Science Foundation

National Natural Science Foundation of China

China ‘12.5’ Innovative Drug Project

Research Grants Council of Hong Kong

Hong Kong Polytechnic University

Publisher

Elsevier BV

Subject

Cell Biology,Cellular and Molecular Neuroscience

Reference51 articles.

1. Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery;Barros;Br. J. Pharmacol,2008

2. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms;Block;Nat. Rev. Neurosci,2007

3. Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease;Blum;Prog. Neurobiol,2001

4. Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes;Bolanos;J. Neurochem,1994

5. Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease;Bretaud;Neurotoxicol. Teratol,2004

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