An abnormal form of purine nucleoside phosphorylase in a family with a child with severe defective T-cell-and normal B-cell immunity
Author:
Publisher
Elsevier BV
Subject
Biochemistry (medical),Clinical Biochemistry,Biochemistry,General Medicine
Reference10 articles.
1. ERYTHROCYTE METABOLISM
2. ENZYMES OF THE HUMAN ERYTHROCYTE
3. Purine Nucleoside Phosphorylase from Human Erythrocytes
4. Inherited variants of human nucleoside phosphorylase
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1. Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies;International Immunopharmacology;2010-07
2. An Approach to the Restoration of T Cell Function in a Purine Nucleoside Phosphorylase Deficient Patient;Ciba Foundation Symposium 68 - Enzyme Defects and Immune Dysfunction;2008-05-30
3. Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777;International Immunopharmacology;2002-06
4. Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)—a novel potent and orally active immunosuppressive agent;International Immunopharmacology;2001-06
5. Evidence for a Pathway Independent from 2'-Deoxyguanosine and Reversible by IL-2 by which Purine Nucleoside Phosphorylase Inhibitors Block T-Cell Proliferation;Scandinavian Journal of Immunology;1994-03
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