Thermostability-assisted limited proteolysis-coupled mass spectrometry for capturing drug target proteins and sites

Author:

Yang Liu,Guo Chen-Wan,Luo Qi-MingORCID,Guo Zi-Fan,Chen Ling,Ishihama YasushiORCID,Li Ping,Yang Hua,Gao WenORCID

Publisher

Elsevier BV

Reference45 articles.

1. Target identification and mechanism of action in chemical biology and drug discovery;Schenone;Nat. Chem. Biol.,2013

2. Target identification for small bioactive molecules: finding the needle in the haystack;Ziegler;Angew. Chem., Int. Ed. Engl.,2013

3. Target identification using drug affinity responsive target stability (DARTS);Lomenick;Proc. Natl. Acad. Sci. U.S.A.,2009

4. Tracking cancer drugs in living cells by thermal profiling of the proteome;Savitski;Science,2014

5. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay;Martinez Molina;Science,2013

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