Quantitative determination of dexamethasone in bovine plasma and tissues by liquid chromatography–atmospheric pressure chemical ionization–tandem mass spectrometry to monitor residue depletion kinetics

Author:

Cherlet Marc,Baere Siegrid De,Croubels Siska,Backer Patrick De

Publisher

Elsevier BV

Subject

Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference19 articles.

1. Dexamethasone, Summary Report, EMEA/MRL/195/97, London, 1997.

2. Detection of corticosteroids in injection sites and cocktails by MSn†

3. EEC Council Directive N° 96/22, Off. J. Eur. Commun. 1996 N° L125.

4. Commission Regulation (EC) N° 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in food stuffs of animal origin (Off. J. Eur. Commun. 1990 N° L224), as amended by Council Regulation N° 2593/99 (Off. J. Eur. Commun. 1999 N° L315).

5. Extract of Draft vol. 8, Notice to applicants, Veterinary medicinal products: Establishment of maximum residue limits (MRLs) for residues of veterinary products in foodstuffs of animal origin: Development and validation of a proposed regulatory method. EMEA/CVMP/573/00-FINAL.

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