Quantification of residual solvents in antibody drug conjugates using gas chromatography

Author:

Medley Colin D.,Kay Jacob,Li Yi,Gruenhagen Jason,Yehl Peter,Chetwyn Nik P.

Publisher

Elsevier BV

Subject

Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference18 articles.

1. Trastuzumab emtansine: a unique antibody-drug conjugate in development of human epidermal growth factor receptor 2 –positive cancer;LoRusso;Clin. Cancer Res.,2011

2. Development of potent monoclonal antibody auristatin conjugates for cancer therapy;Doronina;Nat. Biotechnol.,2003

3. Pneumococcal conjugate vaccines;Peeters;Immunol. Lett.,1991

4. Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite, plasmodium falciparum;Etlinger;J. Immunol.,1988

5. Enhanced epitopic response to a synthetic human malarial peptide by preimmunization with tetanus toxoid carrier;Lise;Infect. Immun.,1987

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