The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation

Author:

Shoji Shisako,Muto Yutaka,Ikeda Mariko,He Fahu,Tsuda Kengo,Ohsawa Noboru,Akasaka Ryogo,Terada Takaho,Wakiyama Motoaki,Shirouzu Mikako,Yokoyama Shigeyuki

Funder

RIKEN BSI Research Resources Center

RIKEN Special Postdoctoral Researcher Program

JSPS KAKENHI

Targeted Proteins Research Program, and the Platform for Drug Discovery, Informatics, and Structural Life Science from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology

Reference78 articles.

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2. The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation;Weissman;Nat. Rev. Mol. Cell Biol.,2011

3. RING domain E3 ubiquitin ligases;Deshaies;Annu. Rev. Biochem.,2009

4. The anaphase promoting complex/cyclosome: a machine designed to destroy;Peters;Nat. Rev. Mol. Cell Biol.,2006

5. Finishing mitosis, one step at a time;Sullivan;Nat. Rev. Mol. Cell Biol.,2007

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