In silico analysis of non-synonymous missense SNPs (nsSNPs) in CPE, GNAS genes and experimental validation in type II diabetes mellitus through Next Generation Sequencing

Author:

Sabiha Bibi,Bhatti Attya,Roomi Sohaib,John Peter,Ali Johar

Funder

National University of Sciences and Technology

Higher Education Commission Pakistan

Publisher

Elsevier BV

Subject

Genetics

Reference69 articles.

1. Beta cell dysfunction and insulin resistance;Cerf;Front. Endocrinol. (Lausanne),2013

2. Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes;Kimple;Exp. Mol. Med.,2014

3. Targeting orphan G protein-coupled receptors for the treatment of diabetes and its complications: C-peptide and GPR146;Kolar;J. Intern. Med.,2017

4. G protein-coupled receptors: abnormalities in signal transmission, disease states and pharmacotherapy;Zalewska;Acta Pol. Pharm.,2014

5. G protein-coupled receptors as disease targets: emerging paradigms;Cook;Ochsner J.,2010

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