Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases

Author:

Burchell Brian,Soars Matt,Monaghan Gemma,Cassidy Andy,Smith Debbie,Ethell Brian

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference52 articles.

1. Neonatal hyperbilirubinaemia and mutation of bilirubin UDP-glucuronosyltransferase gene: a common missense mutation among Japanese, Koreans, Chinese;Akaba;Biochem. Mol. Biol. Int.,1998

2. Amore, B.M., Wynalda, M.A., Hauer, M.J., Fagerness, P.E., Wienkers, L.C., 1998. Human Biotransformation of Broprimine: In vitro characterisation of the primary phase II conjugate of Broprimine. Gordon Conference on Drug Metabolism, Holderness, NH, USA, Abstract B5.

3. The UGT1A1*28 allele is relatively rare in a Japanese population;Ando;Pharmacogenetics,1998

4. Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert’s syndrome;Aono;Lancet,1995

5. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism;Beutler;Proc. Natl. Acad. Sci. USA,1998

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