Could DNA-reactive B lymphocytes be activated through HIV-1 DNA-stimulation involving BCR/TLR-9 pathway to yield antibodies targeting viral DNA?-Reference-Cited by-同舟云学术

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Could DNA-reactive B lymphocytes be activated through HIV-1 DNA-stimulation involving BCR/TLR-9 pathway to yield antibodies targeting viral DNA?

Published:2014-12 Issue:6 Volume:83 Page:659-663
ISSN:0306-9877
Container-title:Medical Hypotheses
language:en
Short-container-title:Medical Hypotheses

Author:

Norelli Sandro

Publisher

Elsevier BV

Subject

General Medicine

Reference30 articles.

1. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation;Chomont;Nat Med,2009

2. Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension;Lewis;AIDS,2011

3. A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model;Shytaj;PLoS Pathog,2012

4. Innate immunity;Medzhitov;N Engl J Med,2000

5. CpG motifs in bacterial DNA trigger direct B-cells activation;Krieg;Nature,1995

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