Significant transcriptional down-regulation of the human MDR1 gene by β-naphthoflavone: A proposed hypothesis linking potent CYP gene induction to MDR1 inhibition-Reference-Cited by-同舟云学术

Significant transcriptional down-regulation of the human MDR1 gene by β-naphthoflavone: A proposed hypothesis linking potent CYP gene induction to MDR1 inhibition

Published:2007-01 Issue:3 Volume:68 Page:661-669
ISSN:0306-9877
Container-title:Medical Hypotheses
language:en
Short-container-title:Medical Hypotheses

Author:

Nwankwo Joseph O.

Publisher

Elsevier BV

Subject

General Medicine

Reference42 articles.

1. Human cytochromes P450 associated with the Phase 1 metabolism of drugs and other xenobiotics: a compilation of substrates and inhibitors of the CYP1, CYP2 and CYP3 families;Lewis;Curr Med Chem,2003

2. Simultaneous measurement of 23 isoforms from the human cytochrome P450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction;Girault;Drug Metab Disp,2005

3. Structure-activity relationships for human cytochrome P450 substrates and inhibitors;Lewis;Drug Metab Rev,2002

4. Modulation of MDR1 and CYP3a expression by dexamethasone: evidence for an inverse regulation in adrenals;Seree;Biochem Biophys Res Commun,1998

5. P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans;Schuetz;Proc Natl Acad Sci USA,1996

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Beta-naphthoflavone and doxorubicin synergistically enhance apoptosis in human lung cancer cells by inducing doxorubicin accumulation, mitochondrial ROS generation, and JNK pathway signaling;Biochemical and Biophysical Research Communications;2022-12

2. Combined Treatment of Dendrosomal-Curcumin and Daunorubicin Synergistically Inhibit Cell Proliferation, Migration and Induce Apoptosis in A549 Lung Cancer Cells;Advanced Pharmaceutical Bulletin;2022-07-02

3. Dioscin Restores the Activity of the Anticancer Agent Adriamycin in Multidrug-Resistant Human Leukemia K562/Adriamycin Cells by Down-Regulating MDR1 via a Mechanism Involving NF-κB Signaling Inhibition;Journal of Natural Products;2013-04-26

4. The Coordinated Role of CYP450 Enzymes and P-gp in Determining Cancer Resistance to Chemotherapy;Current Drug Metabolism;2011-10-01

5. The ability of polycyclic aromatic hydrocarbons to alter physiological factors underlying drug disposition;Drug Metabolism Reviews;2011-08-08