Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation-Reference-Cited by-同舟云学术

Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation

Published:2021-11 Issue: Volume:52 Page:31-47
ISSN:0924-977X
Container-title:European Neuropsychopharmacology
language:en
Short-container-title:European Neuropsychopharmacology

Author:

Targowska-Duda Katarzyna M.,Budzynska Barbara,Michalak Agnieszka,Wnorowski Artur,Loland Claus J.,Maj Maciej,Manetti Dina,Romanelli Maria Novella,Jozwiak Krzysztof,Biala Grazyna,Arias Hugo R.

Publisher

Elsevier BV

Subject

Pharmacology (medical),Biological Psychiatry,Psychiatry and Mental health,Neurology (clinical),Neurology,Pharmacology

Reference51 articles.

1. The role of mTOR in depression and antidepressant responses;Abelaira;Life Sci.,2014

2. α7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice;Alzarea;Behav. Brain Res.,2019

3. Effects of α7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice;Alzarea;Prog Neuropsychopharmacol. Biol. Psychiatry,2018

4. Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective;Andersen;Neuropharmacology,2016

5. Antidepressant-like effects of nicotinic acetylcholine receptor antagonists, but not agonists, in the mouse forced swim and mouse tail suspension tests;Andreasen;J. Psychopharmacol,2009

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chronic administration of caffeine, modafinil, AVL-3288 and CX516 induces time-dependent complex effects on cognition and mood in an animal model of sleep deprivation;Pharmacology Biochemistry and Behavior;2024-08

2. Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation;Experimental Neurology;2024-02

3. Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression;Translational Psychiatry;2024-01-22

4. Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes, via activation of mTORC1 in the medial prefrontal cortex in lipopolysaccharide-induced depression model mice;Nutritional Neuroscience;2023-09-13

5. Pathophysiology of nAChRs: Limbic circuits and related disorders;Pharmacological Research;2023-05