A proof-of-concept study of maternal immune activation mediated induction of Toll-like receptor (TLR) and inflammasome pathways leading to neuroprogressive changes and schizophrenia-like behaviours in offspring

Author:

Talukdar Pinku Mani,Abdul Fazal,Maes Michael,Berk Michael,Venkatasubramanian Ganesan,Kutty Bindu M.,Debnath Monojit

Publisher

Elsevier BV

Subject

Pharmacology (medical),Biological Psychiatry,Psychiatry and Mental health,Neurology (clinical),Neurology,Pharmacology

Reference44 articles.

1. The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring;Arsenault;Brain Behav. Immun.,2014

2. Pattern of expression of Toll like receptor (TLR)-3 and -4 genes in drug-naive and antipsychotic treated patients diagnosed with schizophrenia;Balaji;Psychiatry Res.,2020

3. Brain changes in a maternal immune activation model of neurodevelopmental brain disorders;Bergdolt;Prog. Neurobiol.,2019

4. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors;Berk;Neurosci. Biobehav. Rev.,2011

5. Associations Between Maternal Infection During Pregnancy, Childhood Infections, and the Risk of Subsequent Psychotic Disorder–A Swedish Cohort Study of Nearly 2 Million Individuals;Blomstrom;Schizophr. Bull.,2016

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