Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling

Author:

Li Hongyuan,Peng Yinghua,Lin Cong,Zhang Xiaozheng,Zhang Tianshu,Wang YiboORCID,Li Yuanpeng,Wu Siru,Wang Hongshuang,Hutchinson Mark R.,Watkins Linda R.,Wang XiaohuiORCID

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference38 articles.

1. Pattern recognition receptors and inflammation;Takeuchi;Cell,2010

2. Small-molecule modulators of toll-like receptors;Wang;Acc. Chem. Res.,2020

3. Research progress in the development of nicotine as a medicine;Li;Prog. Pharm. Sci.,2019

4. Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action;Park;Eur. J. Neurosci.,2007

5. A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia;Lutz;Fitoterapia,2014

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