Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop
Author:
Funder
University of Texas at San Antonio
University of Texas Health Science Center at San Antonio
National Institutes of Health
George Washington University
Publisher
Elsevier BV
Subject
Multidisciplinary
Reference31 articles.
1. Increased risk of locoregional recurrence for women with T1-2N0 triple-negative breast cancer treated with modified radical mastectomy without adjuvant radiation therapy compared with breast-conserving therapy;Abdulkarim;J. Clin. Oncol.,2011
2. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation;Bakkenist;Nature,2003
3. ATM, ATR, and DNA-PK: the trinity at the heart of the DNA damage response;Blackford;Mol. Cell,2017
4. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks;Cortez;Science,1999
5. Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo;Daniel;J. Cell Biol.,2008
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Genomic Features of Homologous Recombination Deficiency in Breast Cancer: Impact on Testing and Immunotherapy;Genes;2024-01-26
2. DON induced DNA damage triggers absence of p53-mediated G2 arrest and apoptosis in IPEC-1 cells;Toxicology;2024-01
3. Arsenite Impairs BRCA1-Dependent DNA Double-Strand Break Repair, a Mechanism Potentially Contributing to Genomic Instability;International Journal of Molecular Sciences;2023-09-21
4. The mechanism and clinical application of DNA damage repair inhibitors combined with immune checkpoint inhibitors in the treatment of urologic cancer;Frontiers in Cell and Developmental Biology;2023-05-25
5. PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1;Cell Reports;2023-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3