HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells-Reference-Cited by-同舟云学术

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells

Published:2019-06 Issue: Volume:16 Page:192-205
ISSN:2589-0042
Container-title:iScience
language:en
Short-container-title:iScience

Author:

Ng Natasha Hui Jin,Jasmen Joanita Binte,Lim Chang Siang,Lau Hwee Hui,Krishnan Vidhya Gomathi,Kadiwala Juned,Kulkarni Rohit N.,Ræder Helge,Vallier Ludovic,Hoon Shawn,Teo Adrian Kee Keong^ORCID

Funder

National Medical Research Council

Open Fund-Young Individual Research

National Institutes of Health

Bergen Forskningsstiftelse (BFS)

Western Norway Regional Health Authority

Novo Nordisk Foundation

Diabetesforbundet

ERC

National Institute for Health Research Biomedical Research Centre

Wellcome Trust and Medical Research Council

Wellcome–Medical Research Council Cambridge Stem Cell Institute

Institute of Molecular and Cell Biology

A*STAR

Lee Foundation

Skin Innovation

Precision Medicine and Personalised Therapeutics Joint Research

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference58 articles.

1. FGF2 specifies hESC-derived definitive endoderm into foregut/midgut cell lineages in a concentration-dependent manner;Ameri;Stem Cells,2010

2. The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms;Balbinot;J. Exp. Med.,2018

3. Cell-autonomous and non-cell-autonomous function of hox genes specify segmental neuroblast identity in the gnathal region of the embryonic CNS in Drosophila;Becker;PLoS Genet.,2016

4. Epistasis of transcriptomes reveals synergism between transcriptional activators Hnf1α and Hnf4α;Boj;PLoS Genet.,2010

5. Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays;Bolotin;Hepatology,2010

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Polyploidisation pleiotropically buffers ageing in hepatocytes;Journal of Hepatology;2024-08

2. CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant;Cell Reports;2024-08

3. Directed differentiation of pancreatic δ cells from human pluripotent stem cells;Nature Communications;2024-07-27

4. HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes;Nature Communications;2024-06-22

5. CRISPR Screening Uncovers a Long-Range Enhancer forONECUT1in Pancreatic Differentiation and Links a Diabetes Risk Variant;2024-04-29