New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets-Reference-Cited by-同舟云学术

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New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

Published:2024-05 Issue:5 Volume:27 Page:109777
ISSN:2589-0042
Container-title:iScience
language:en
Short-container-title:iScience

Author:

Giannelli Serena Gea,Luoni Mirko,Iannielli Angelo,Middeldorp Jinte,Philippens Ingrid,Bido Simone,Körbelin Jakob,Broccoli Vania^ORCID

Funder

European Commission

Publisher

Elsevier BV

Reference50 articles.

1. The clinical landscape for AAV gene therapies;Kuzmin;Nat. Rev. Drug Discov.,2021

2. Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality;Hudry;Neuron,2019

3. Gene therapy for neurological disorders: progress and prospects;Deverman;Nat. Rev. Drug Discov.,2018

4. Viral Strategies for Targeting the Central and Peripheral Nervous Systems;Bedbrook;Annu. Rev. Neurosci.,2018

5. Adeno-Associated Virus-Based Gene Therapy for CNS Diseases;Hocquemiller;Hum. Gene Ther.,2016

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