MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors-Reference-Cited by-同舟云学术

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MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors

Published:2024-06 Issue:6 Volume:27 Page:109862
ISSN:2589-0042
Container-title:iScience
language:en
Short-container-title:iScience

Author:

Ingelshed Katrine,Melssen Marit M.,Kannan Pavitra,Chandramohan Arun,Partridge Anthony W.,Jiang Long,Wermeling Fredrik,Lane David P.,Nestor Marika,Spiegelberg Diana^ORCID

Funder

Swedish Cancer Society

Publisher

Elsevier BV

Reference61 articles.

1. p53 in health and disease;Vousden;Nat Rev Mol. Cell Bio.,2007

2. MDM2 and MDMX: Alone and together in regulation of p53;Shadfan;Transl. Cancer Res.,2012

3. Stabilization of the MDM2 Oncoprotein by Interaction with the Structurally Related MDMX Protein;Sharp;J. Biol. Chem.,1999

4. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo;Yang;Cancer Res.,2021

5. The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo;Huang;Proc. Natl. Acad. Sci. USA,2011

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