A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH-Reference-Cited by-同舟云学术

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A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH

Published:2017-10 Issue: Volume:216-217 Page:86-90
ISSN:2210-7762
Container-title:Cancer Genetics
language:en
Short-container-title:Cancer Genetics

Author:

Sadras Teresa,Heatley Susan L.,Kok Chung H.,McClure Barbara J.,Yeung David,Hughes Timothy P.,Sutton Rosemary,Ziegler David S.,White Deborah L.

Funder

National Health and Medical Research Council

Leukaemia Foundation

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology

Reference15 articles.

1. Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome;Harvey;Blood,2010

2. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group;Hertzberg;Blood,2010

3. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia;Russell;Blood,2009

4. Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia;Yoda;Proc Natl Acad Sci USA,2010

5. Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2;van Bodegom;Blood,2012

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1. RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL);PLOS Genetics;2022-10-17

2. JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies;Frontiers in Cell and Developmental Biology;2022-07-12

3. Resistance Mechanisms in Pediatric B-Cell Acute Lymphoblastic Leukemia;International Journal of Molecular Sciences;2022-03-12

4. Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia;npj Precision Oncology;2021-08-10

5. Thrombocytosis in children and adolescents—classification, diagnostic approach, and clinical management;Annals of Hematology;2021-03-12

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