A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease-Reference-Cited by-同舟云学术

A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease

Published:2004-02 Issue:1-2 Volume:121 Page:141-145
ISSN:0169-328X
Container-title:Molecular Brain Research
language:en
Short-container-title:Molecular Brain Research

Author:

Murphy Robert C.,Messer Anne

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Reference25 articles.

1. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid;Beal;J. Neurosci.,1993

2. Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine;Calabresi;J. Neurosci.,2001

3. Function of microglia in organotypic slice cultures;Czapiga;J. Neurosci. Res.,1999

4. Misfolded, protease-resistant proteins in animal models and human neurodegenerative disease;Dickson;J. Clin. Invest.,2002

5. Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice;Gines;Hum. Mol. Genet.,2003

Cited by 53 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Emerging Therapies for Huntington’s Disease – Focus on N-Terminal Huntingtin and Huntingtin Exon 1;Biologics: Targets and Therapy;2022-09

2. Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers;International Journal of Molecular Sciences;2020-11-24

3. POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research;Biomolecules;2020-07-20

4. Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases;Pharmaceutics;2020-06-09

5. Downregulation of α-Synuclein Protein Levels by an Intracellular Single-Chain Antibody;Journal of Parkinson's Disease;2020-04-03