TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43

Author:

Godoy-Corchuelo Juan M.,Ali Zeinab,Brito Armas Jose M.,Martins-Bach Aurea B.,García-Toledo Irene,Fernández-Beltrán Luis C.,López-Carbonero Juan I.,Bascuñana Pablo,Spring Shoshana,Jimenez-Coca Irene,Muñoz de Bustillo Alfaro Ramón A.,Sánchez-Barrena Maria J.,Nair Remya R.,Nieman Brian J.,Lerch Jason P.,Miller Karla L.,Ozdinler Hande P.,Fisher Elizabeth M.C.,Cunningham Thomas J.,Acevedo-Arozena Abraham,Corrochano Silvia

Funder

Wellcome Trust

Carlos III Health Institute

Ministerio de Ciencia e Innovación

Community of Madrid Department of Education Science and Universities

Publisher

Elsevier BV

Reference72 articles.

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2. Early cognitive/social deficits and late motor phenotype in conditional wild-type TDP-43 transgenic mice;Alfieri;Front. Aging Neurosci.,2016

3. Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations;Ali;Dis. Model. Mech.,2023

4. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer’s disease;Amador-Ortiz;Ann. Neurol.,2007

5. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis;Arai;Biochem. Biophys. Res. Commun.,2006

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