New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease

Author:

Sergeant NicolasORCID,Vingtdeux Valérie,Eddarkaoui Sabiha,Gay Marion,Evrard Caroline,Le Fur Nicolas,Laurent Cyril,Caillierez Raphaelle,Obriot Hélène,Larchanché Paul-Emmanuel,Farce Amaury,Coevoet Mathilde,Carato Pascal,Kouach Mostafa,Descat Amandine,Dallemagne Patrick,Buée-Scherrer Valérie,Blum David,Hamdane Malika,Buée Luc,Melnyk PatriciaORCID

Funder

Agence Nationale de la Recherche

Publisher

Elsevier BV

Subject

Neurology

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3. Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease;Barsuto-Islas;J. Biol. Chem.,2013

4. Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease;Belarbi;Curr. Alzheimer Res.,2009

5. Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology;Belarbi;Neurobiol. Dis.,2011

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