Heterozygous loss of Engrailed-1 and α-synucleinopathy (En1/SYN): A dual-hit preclinical mouse model of Parkinson's disease, analyzed with artificial intelligence

Author:

Stetzik Lucas,Mercado Gabriela,Steiner Jennifer A.,Lindquist Allison,Gilliland Carla,Schulz Emily,Meyerdirk Lindsay,Smith Lindsey,Molina Jeremy,Moore Darren J.

Funder

NIH

Publisher

Elsevier BV

Reference28 articles.

1. Abonce, S.E.V., Lebœuf, M., Moya, K.L., Prochiantz, A., 2019. The homeoprotein ENGRAILED-1 promotes motoneuron survival and motor functions. biorxiv 734020. Version3 March 20, 2020.

2. Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex i insults;Alvarez-Fischer;Nat. Neurosci.,2011

3. Parkinson’s disease: a model dilemma;Beal;Nature,2010

4. Mechanisms of peripheral levodopa resistance in Parkinson’s disease;Beckers;NPJ Parkinsons Dis.,2022

5. Comprehensive catwalk gait analysis in a chronic model of multiple sclerosis subjected to treadmill exercise training;Bernardes;BMC Neurol.,2017

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