Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson's disease

Author:

Ikeda-Matsuo YuriORCID,Miyata Hajime,Mizoguchi Tomoko,Ohama Eisaku,Naito Yasuhito,Uematsu Satoshi,Akira Shizuo,Sasaki Yasuharu,Tanabe Mitsuo

Funder

KAKENHI

Uehara Memorial Foundation

Publisher

Elsevier BV

Subject

Neurology

Reference43 articles.

1. PGE(2) EP1 Receptor Deletion Attenuates 6-OHDA-Induced Parkinsonism in mice: Old Switch, New Target;Ahmad;Neurotox. Res.,2013

2. Nonsteroidal anti-inflammatory drugs in Parkinson's disease: possible involvement of quinone formation;Asanuma;Expert. Rev. Neurother.,2006

3. Aggregation of α-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies;Baba;Am. J. Pathol.,1998

4. NF-kappaB induces PGE2-synthesizing enzymes in neurons;Barakat;Naunyn Schmiedeberg's Arch. Pharmacol.,2009

5. Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile;Boulet;J. Biol. Chem.,2004

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