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The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease

  • Published:2021-06 Issue: Volume:153 Page:105312
  • ISSN:0969-9961
  • Container-title:Neurobiology of Disease
  • language:en
  • Short-container-title:Neurobiology of Disease

Author:

De Miranda Briana R.,Castro Sandra L.,Rocha Emily M.,Bodle Christopher R.,Johnson Katrina E.,Greenamyre J. Timothy

Funder

Parkinson's Disease Foundation Inc

American Parkinson Disease Association

National Institutes of Health

Michael J Fox Foundation for Parkinson's Research

National Institute of Environmental Health Sciences

Publisher

Elsevier BV

Subject

Neurology

Reference69 articles.

1. Toxicological Profile for Trichloroethylene (TCE);Agency for Toxic Substances and Disease Registry (ATSDR).,2019

2. LRRK2 kinase in Parkinson's disease;Alessi;Science,2018

3. Pesticide exposure and risk for Parkinson's disease;Ascherio;Ann. Neurol.,2006

4. LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation;Bae;Nat. Commun.,2018

5. Pesticides exposure as etiological factors of Parkinson’s disease and other neurodegenerative diseases—a mechanistic approach;Baltazar;Toxicol. Lett.,2014

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