The same TCR (N)Dβ(N)Jβ junctional region is associated with several different vβ13 subtypes in a multiple sclerosis patient at the onset of the disease

Author:

Démoulins Thomas,Mouthon Franck,Clayette Pascal,Bequet Daniel,Gachelin Gabriel,Dormont Dominique

Publisher

Elsevier BV

Subject

Neurology

Reference43 articles.

1. Human T-cell receptor variable gene segment families;Arden;Immunogenetics,1995

2. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction;Babbe;J. Exp. Med.,2000

3. Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis;Ben-Nun;Proc. Natl. Acad. Sci. USA,1991

4. Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo;Bour;J. Immunol.,1999

5. Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes;Bourdette;J. Immunol.,1998

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