Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo
Author:
Publisher
Elsevier BV
Subject
Neurology
Reference43 articles.
1. In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase;Behndig;Free Radical Biol. Med.,2001
2. Induction of an interferon response by RNAi vectors in mammalian cells;Bridge;Nat. Genet.,2003
3. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS);Dal Canto;Brain Res.,1995
4. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis;Ding;Aging Cell,2003
5. siRNA relieves chronic neuropathic pain;Dorn;Nucleic Acids Res.,2004
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