Axons are injured by antigen-specific CD8+ T cells through a MHC class I- and granzyme B-dependent mechanism-Reference-Cited by-同舟云学术

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Axons are injured by antigen-specific CD8+ T cells through a MHC class I- and granzyme B-dependent mechanism

Published:2013-11 Issue: Volume:59 Page:194-205
ISSN:0969-9961
Container-title:Neurobiology of Disease
language:en
Short-container-title:Neurobiology of Disease

Author:

Sauer Brian M.,Schmalstieg William F.,Howe Charles L.

Funder

Donald and Frances Herdrich

United States National Multiple Sclerosis Society

Mayo Foundation for Medical Research

United States National Institutes of Health Medical Scientist Training Program

Publisher

Elsevier BV

Subject

Neurology

Reference63 articles.

1. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction;Babbe;J. Exp. Med.,2000

2. T cell recognition of self-antigen presenting cells by protein transfer assay reveals a high frequency of anti-myelin T cells in multiple sclerosis;Bahbouhi;Brain,2010

3. Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis;Bien;Ann. Neurol.,2002

4. Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation;Bitsch;Brain,2000

5. Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences;Bjartmar;Curr. Opin. Neurol.,2001

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3. Candidate Genetic and Molecular Drivers of Dysregulated Adaptive Immune Responses After Traumatic Brain Injury;Journal of Neurotrauma;2024-01-01

4. CD8+ T cells recognizing a neuron-restricted antigen injure axons in a model of multiple sclerosis;Journal of Clinical Investigation;2023-11-01

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