Prodrugs as drug delivery systems. 65. Hydrolysis of α-hydroxy-and α-acyloxy-N-benzoylglycine derivatives and implications for the design of prodrugs of NH-acidic compounds-Reference-Cited by-同舟云学术

Prodrugs as drug delivery systems. 65. Hydrolysis of α-hydroxy-and α-acyloxy-N-benzoylglycine derivatives and implications for the design of prodrugs of NH-acidic compounds

Published:1987-07 Issue:3 Volume:37 Page:185-194
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Bundgaard Hans,Buur Anders

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference26 articles.

1. The reactions of ureas with glyoxylic acid and methyl glyoxylate;Ben-Ishai;Tetrahedron,1191

2. A new synthesis of amino acids. II. Amidoalkylation of olefins with glyoxylic acid derivatives;Ben-Ishai;Tetrahedron,1533

3. Novel approaches in prodrug design;Bodor;Drugs Future

4. Design of prodrugs: bioreversible derivatives for various functional groups and chemical entities;Bundgaard,1985

5. Prodrugs as drug delivery systems. VIII. Bioreversible derivatization of hydantoins by N-hydroxymethylation;Bundgaard;Int. J. Pharm.,1980

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