Structure-activity relationships in verapamil and analogues using molecular mechanics calculations

Author:

Fernández Berta,Mosquera Ricardo,Uriarte Eugenio

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference14 articles.

1. Structure of α-isopropyl-α-[(N-methyl-N-homoveratryl)-γ-aminopropyl]-3,4-dimethoxyphenylacetonitrile hydrochloride. Verapamil;Carpy;Acta Crystallogr. Sect C: Cryst. Struct. Commun.,1985

2. Zum Wirkungs-Mechanismus neuartiger Koronardilatoren mit gleichzeitig Sauerstoff-einsparenden, miokard-Effekten, Prenylamin und Iproveratril;Fleckenstein;Z. Kreislaufforsch.,1967

3. SAR Studies in the field of calcium(II) antagonists. Effect of modifications at the tetrasubstituted carbon of verapamil-like compounds;Gualteri;J. Med. Chem.,1985

4. α-Isopropyl-α-[γ-(N-methyl-N-homoveratrylamino)propyl]-3,4-dimethoxyphenylacetonitrile, a compound with coronary-dilating activity;Haas;Arzneimittel-Forschung,1962

5. Theoretical investigations of interactions of verapamil derivatives;Holtje;Arch. Pharm.,1983

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