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Allopurinol prodrugs. II. Synthesis, hydrolysis kinetics and physicochemical properties of various N-acyloxymethyl allopurinol derivatives

  • Published:1985-05 Issue:2-3 Volume:24 Page:307-325
  • ISSN:0378-5173
  • Container-title:International Journal of Pharmaceutics
  • language:en
  • Short-container-title:International Journal of Pharmaceutics

Author:

Bundgaard Hans,Falch Erik

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference38 articles.

1. The Determination of lonization Constants;Albert,1971

2. Allopurinol absorption from rectal suppositories;Appelbaum;Drag Intell. Clin. Pharm.,1980

3. Allopurinol kinetics and bioavailability. Intravenous, oral and rectal administration;Appelbaum;Cancer Chemother. Pharmacol.,1982

4. N-Hydroxymethyl derivatives of nitrogen heterocycles as possible prodnugs II: Possible prodrugs of allopurinol, glutethimide and phenobarbital;Bansal;J. Pharm. Sci.,1981

5. Studies on the chemical reactivity and the physical properties of allopurinol (pyrazolo[3,4-d]pyrimidin-4-one) and related compounds;Bergmann;J. Chem. Soc. Perkin Trans.,1979

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1. Synthesis and pharmaceutical properties of N-acyloxymethyl prodrugs of Allop with potential anti-trypanosomal activity;Drug Development and Industrial Pharmacy;2015-07-16

2. Enzymatic Synthesis of 2′-Deoxy-β-d-ribonucleosides of 8-Azapurines and 8-Aza-7-deazapurines;Synlett;2012-05-29

3. References;Handbook of Aqueous Solubility Data, Second Edition;2010-04-26

4. References;Handbook of Aqueous Solubility Data, Second Edition;2010-04-26

5. Prodrugs for Improved Aqueous Solubility;Water-Insoluble Drug Formulation, Second Edition;2008-01-18
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