Resistance to enzymic hydrolysis as a parameter in drug potency

Author:

Cheung Y.W.,Li Wan Po A.,Irwin W.J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference19 articles.

1. Studies on the stability of corticosteroids. VI. kinetics of the rearrangement of betamethasone-17-valerate to the 21-valerate ester in aqueous solution;Bundgaard;Int. J. Pharm.,1981

2. Cutaneous biotransformation as a parameter in the modulation of the activity of topical cortiscosteroids;Cheung;Int. J. Pharm.,1985

3. Sulindac: therapeutic implication of the prodrug/pharmacophore equilibrium;Duggan;Drug Metab. Rev.,1981

4. Derivati di condensazione nella catena laterale di cortiscosteroidi Nota. III. Preparatione e reazioni dei 17-monoesteri;Gardi;Gazz. Chim. Ital.,1963

5. The in vivo catabolism of cortisol by human skin;Greaves;J. Invest. Dermatol.,1971

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1. Medicinal Uses of Modified Hyaluronate;Chemistry and Biology of Hyaluronan;2004

2. Pharmacokinetics and ‘bioactivation’ of MPA;Journal of the European Academy of Dermatology and Venereology;1994-04

3. Enzymic and non-enzymic hydrolysis of a polymeric prodrug: Hydrocortisone esters of hyaluronic acid;International Journal of Pharmaceutics;1992-05

4. Comparison of enzymic activities of tissues lining portals of drug absorption, using the rat as a model;International Journal of Pharmaceutics;1990-07

5. Prodrugs for dermal delivery;International Journal of Pharmaceutics;1989-10

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