Improved distribution and reduced toxicity of adriamycin bound to albumin-heparin microspheres

Author:

Cremers H.F.M.,Verrijk R.,Bayon L.G.,Wesseling M.M.,Wondergem J.,Heuff G.,Meijer S.,Kwon G.S.,Bae Y.H.,Kim S.W.,Feijen J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference18 articles.

1. Doxorubicin: Effect of different schedules on toxicity and anti-tumor efficacy;Bielack;Eur. J. Cancer Clin. Oncol.,1989

2. Adriamycin causes hyperlipidemia as a consequence of nephrotoxicity;Bizzi;Toxicol. Lett.,1983

3. Epirubicin and doxorubicin comparative metabolism and pharmacokinetics;Camaggi;Cancer Chemother. Pharmacol.,1988

4. Reduced toxicity of adriamycin by incorporation into ion exchange microspheres: A therapeutic study using a rat liver tumour model;Codde;Anticancer Res.,1990

5. Preparation and characterization of albumin-heparin microspheres;Cremers;Biomaterials,1994

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