Relationship between hydrophobicity and biological activities of xanthine derivatives in guinea pig tracheal smooth muscle

Author:

Takaaki Hasegawa,Kenichi Miyamoto,Shinya Wakusawa,Kenzo Takagi,Ruttikorn Apichartpichean,Takafumi Kuzuya,Masayuki Nadai,Tadashi Horiuchi

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference24 articles.

1. Studies on alkyl-xanthine derivatives. II. Pharmacokinetic and pharmacodynamic studies of a new bronchodilator, 1-methyl-3-propylxanthine (MPX);Apichartpichean;Jap. J. Pharmacol,1988

2. Effects of verapamil on the contractions of guinea-pig tracheal muscle induced by Ca, Sr, and Ba;Baba;Br. J. Pharmacol.,1985

3. Evidence that the positive inotropic effects of the alkylxanthines are not due to adenosine receptor blockage;Collis;Br. J. Pharmacol.,1984

4. The determination of enzyme inhibitor constants;Dixon;Biochem. J.,1953

5. Xanthine derivatives as adenosine receptor antagonists;Fredholm;Eur. J. Pharmacol.,1982

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