SR-12813 lowers plasma cholesterol in beagle dogs by decreasing cholesterol biosynthesis-Reference-Cited by-同舟云学术

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SR-12813 lowers plasma cholesterol in beagle dogs by decreasing cholesterol biosynthesis

Published:1997-09 Issue:2 Volume:133 Page:203-212
ISSN:0021-9150
Container-title:Atherosclerosis
language:en
Short-container-title:Atherosclerosis

Author:

Berkhout Theo A,Simon Helen M,Jackson Brian,Yates John,Pearce Nigel,Groot Pieter H.E,Bentzen Craig,Niesor Eric,Kerns William D,Suckling Keith E

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference32 articles.

1. SKF 99085/SR-9223i, a novel hypocholesterolemic agent with multiple anti-atherosclerotic properties, lowers plasma cholesterol in normocholesterolemic animals;Suckling;Atherosclerosis,1994

2. SKF 99085/SR-9223i, a novel hypocholesterolemic agent with multiple anti-atherosclerotic properties suppresses HMG-CoA reductase and induces LDL receptor activity by a novel mechanism;Berkhout;Atherosclerosis,1994

3. The novel cholesterol lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of HMG-CoA reductase;Berkhout;J Biol Chem,1996

4. Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase;Tsujita;Atherosclerosis,1979

5. Cholestyramine in dogs;Jansen;J Pharm Sci,1965

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1. HMG-CoA reductase degrader, SR-12813, counteracts statin-induced upregulation of HMG-CoA reductase and augments the anticancer effect of atorvastatin;Biochemical and Biophysical Research Communications;2023-10

2. Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein;Proceedings of the National Academy of Sciences;2023-02-27

3. Fine-tuning of nitrogen-containing bisphosphonate esters that potently induce degradation of HMG-CoA reductase;Bioorganic & Medicinal Chemistry;2023-01

4. Bisphosphonate esters interact with HMG-CoA reductase membrane domain to induce its degradation;Bioorganic & Medicinal Chemistry;2020-07

5. Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols;Bioorganic & Medicinal Chemistry;2020-02

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