A senolytic immunotoxin eliminates p16-positive T cells and ameliorates age-associated phenotypes of CD4+ T cells in a surface marker knock-in mouse-Reference-Cited by-同舟云学术

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A senolytic immunotoxin eliminates p16-positive T cells and ameliorates age-associated phenotypes of CD4+ T cells in a surface marker knock-in mouse

Published:2023-04 Issue: Volume:174 Page:112130
ISSN:0531-5565
Container-title:Experimental Gerontology
language:en
Short-container-title:Experimental Gerontology

Author:

Sugiyama Yuma,Harada Tanenobu,Kamei Yuka,Yasuda Tomoharu,Mashimo Tomoji,Nishikimi Akihiko,Maruyama Mitsuo

Funder

Hori Sciences and Arts Foundation

National Center for Geriatrics and Gerontology

Japan Society for the Promotion of Science

Toyo University

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Genetics,Molecular Biology,Aging,Biochemistry

Reference31 articles.

1. Senolytic CAR T cells reverse senescence-associated pathologies;Amor;Nature,2020

2. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders;Baker;Nature,2011

3. Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan;Baker;Nature,2016

4. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor;Coppé;PLoS Biol.,2008

5. The senescence-associated secretory phenotype: the dark side of tumor suppression;Coppé;Annu. Rev. Pathol.,2010

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Benefit delayed immunosenescence by regulating CD4⁺T cells: A promising therapeutic target for aging‐related diseases;Aging Cell;2024-08-18

2. Senotherapeutic effect of Agrimonia pilosa Ledeb. in targeting senescent cells in naturally aged mice;Food Bioscience;2024-06

3. Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach;Aging and disease;2024

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