Determination and pharmacokinetic study of two triterpenoid saponins in rat plasma after oral administration of the extract of Aralia elata leaves by UHPLC–ESI

Determination and pharmacokinetic study of two triterpenoid saponins in rat plasma after oral administration of the extract of Aralia elata leaves by UHPLC–ESI–MS/MS

Published:2015-03 Issue: Volume:985 Page:164-171
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Wang Zhibin,Wu Qiong,Meng Yonghai,Sun Yichun,Wang Qi,Yang Chunjuan,Wang Qiuhong,Yang Bingyou,Kuang Haixue

Funder

Ministry of Science and Technology of the People's Republic of China

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference25 articles.

1. Two New Saponins, Congmuyenosides A and B, from the Leaves of Aralia elata Collected in Heilongjiang, China.

2. Triterpene Glucosides from the Leaves ofAralia elataand Their Cytotoxic Activities

3. Analysis of Saponins from Leaves of Aralia elata by Liquid Chromatography and Multi-stage Tandem Mass Spectrometry

4. Effect of the total saponins of Aralia elata (Miq) Seem on cardiac contractile function and intracellular calcium cycling regulation

5. Triterpenoid saponin, oleanolic acid 3-O-β-d-glucopyranosyl(1→3)-α-l-rhamnopyranosyl(1→2)-α-l-arabinopyranoside (OA) from Aralia elata inhibits LPS-induced nitric oxide production by down-regulated NF-κB in raw 264.7 cells

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