In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC–ECNICI-MS analysis-Reference-Cited by-同舟云学术

In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC–ECNICI-MS analysis

Published:2011-05 Issue:17-18 Volume:879 Page:1476-1484
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Tsikas Dimitrios,Trettin Arne,Zörner Alexander A.,Gutzki Frank-Mathias

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference28 articles.

1. ACETAMINOPHEN-INDUCED HEPATOTOXICITY

2. Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS

3. The Biochemistry of Drug Metabolism - An Introduction

4. N-Hydroxylation of p-acetophenetidide as a factor in nephrotoxicity

5. Evidence for the involvement of N-ACETYL-p-quinoneimine in acetaminophen metabolism

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