Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC–MS/MS-Reference-Cited by-同舟云学术

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Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC–MS/MS

Published:2014-12 Issue: Volume:973 Page:68-75
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Zhou Yunfang,Wang Shuanghu,Ding Ting,Chen Mengchun,Wang Li,Wu Mingdong,Hu Guoxin,Lu Xianghong

Funder

National Health and Family Planning Commission of the People's Republic of China

Association of Integrated Traditional and Western Medicine Research Project of Zhejiang Province

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference30 articles.

1. Summary of information on human CYP enzymes: human P450 metabolism data

2. The physiological and pharmacological roles of cytochrome P450 isoenzymes

3. Cathepsin B: a potential prognostic marker for inflammatory breast cancer

4. Effects of capsaicin and dihydrocapsaicin on human and rat liver microsomal CYP450 enzyme activitiesin vitroandin vivo

5. Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC–DAD: A cocktail approach

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1. Inhibitory effects of the main metabolites of Apatinib on CYP450 isozymes in human and rat liver microsomes;Toxicology in Vitro;2024-03

2. Pharmacokinetics of Dasatinib in Rats: a Potential Food–Drug Interaction with Naringenin;European Journal of Drug Metabolism and Pharmacokinetics;2024-02-20

3. The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism;PeerJ;2023-12-08

4. CYP2D6 gene polymorphism and apatinib affect the metabolic profile of fluvoxamine;Frontiers in Pharmacology;2022-09-02

5. Application of Physiologically Based Pharmacokinetic Modeling in Preclinical Studies: A Feasible Strategy to Practice the Principles of 3Rs;Frontiers in Pharmacology;2022-05-12

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