Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC

Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC–MS/MS

Published:2009-12 Issue:31 Volume:877 Page:4001-4006
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Farnik Harald,El-Duweik Juliane,Welsch Christoph,Sarrazin Christoph,Lötsch Jörn,Zeuzem Stefan,Geisslinger Gerd,Schmidt Helmut

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference11 articles.

1. Viral hepatitis C

2. Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

3. Discovery of Small-Molecule Inhibitors of HCV NS3-4A Protease as Potential Therapeutic Agents against HCV Infection

4. SCH 503034, a Mechanism-Based Inhibitor of Hepatitis C Virus NS3 Protease, Suppresses Polyprotein Maturation and Enhances the Antiviral Activity of Alpha Interferon in Replicon Cells

5. S. Susser, C. Welsch, Y. Wang, M. Zettler, F.S. Domingues, U. Karey, E. Hughes, R. Ralston, X. Tong, E. Herrmann, S. Zeuzem, C. Sarrazin, Hepatology. (2009) Aug 4. [Epub ahead of print].

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