Simultaneous quantitative determination of 5-aza-2′-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors-Reference-Cited by-同舟云学术

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Simultaneous quantitative determination of 5-aza-2′-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors

Published:2016-06 Issue: Volume:1022 Page:38-45
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Anders Nicole M.,Liu Jianyong,Wanjiku Teresia,Giovinazzo Hugh,Zhou Jianya,Vaghasia Ajay,Nelson William G.,Yegnasubramanian Srinivasan,Rudek Michelle A.

Funder

Celgene Corporation

Flight Attendants Medical Research Institution

Prostate Cancer Foundation Challenge

Commonwealth Foundation

Analytical Pharmacology Core

National Center for Advancing Translational Sciences

National Institutes of Health

NIH Roadmap for Medical Research

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference28 articles.

1. Gene silencing in cancer in association with promoter hypermethylation;Herman;N. Engl. J. Med.,2003

2. The epigenomics of cancer;Jones;Cell,2007

3. The clinical application of targeting cancer through histone acetylation and hypomethylation;Gilbert;Clin. Cancer Res.,2004

4. Operating on chromatin, a colorful language where context matters;Gardner;J. Mol. Biol.,2011

5. Concise drug review: azacitidine and decitabine;Derissen;Oncologist,2013

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1. Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance;2024-05-21

2. DNA methyltransferase inhibitor exposure–response: Challenges and opportunities;Clinical and Translational Science;2023-06-21

3. Oxidative Stress Biomarker Levels of Simulated Artificial Body Fluids: Comparative HPLC-PDA and LC–MS/MS Approaches: Significance of Raw PDA and MS/MS Data for Chemometric Discrimination;Journal of Chromatographic Science;2022-04-18

4. Paradoxical whole genome DNA methylation dynamics of 5’aza-deoxycytidine in chronic low-dose exposure in mice;Epigenetics;2020-07-11

5. Tracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion;Scientific Reports;2019-03-14

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