Development of an efficient LC-MS peptide mapping method using accelerated sample preparation for monoclonal antibodies

Author:

Jiang Ping,Li Fumin,Ding Jie

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference22 articles.

1. Therapeutic antibodies: past, present and future;Leavy;Nat. Rev. Immunol.,2010

2. Therapeutic applications of monoclonal antibodies;Berger;A. J. Med. Sci.,2002

3. Wang Yi, Li Xiaojuan, Liu Yan-Hui, Richardson Daisy, Li Huijuan, Shameem Mohammed, Yang Xiaoyu. Simultaneous monitoring of oxidation, deamidatiojn, isomerization, and glycation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast tryptic digestion. mAbs. 8 (2016) 1477–1486.

4. Post-translational structural modifications of immunoglobulin G and their effect on biological activity;Hmiel;Anal. Bioanal. Chem.,2015

5. Impact of methionine oxidation on the binding of human IgG1 to Fc Rn and Fc gamma receptors;Bertolotti-Ciarlet;Mol. Immunol.,2009

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