Rapid, sensitive, and reliable quantitation of nicotine and its main metabolites cotinine and trans-3′-hydroxycotinine by LC-MS/MS: Method development and validation for human plasma

Author:

Mallock NadjaORCID,Rabenstein Andrea,Laux Peter,Rüther Tobias,Hutzler Christoph,Parr Maria Kristina,Luch Andreas

Funder

Bundesinstitut für Risikobewertung

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference43 articles.

1. Nicotine Chemistry metabolism and kinetics;Benowitz;Handb Exp Pharmacol,2009

2. Metabolism and Disposition Kinetics of Nicotine;Hukkanen;Pharmacol. Rev.,2005

3. Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: A review;Le Houezec;Int. J. Tuberc. Lung. Dis.,2003

4. Public health consequences of e-cigarette use;St Helen;JAMA Intern. Med.,2018

5. A framework for evaluating the public health impact of e-cigarettes and other vaporized nicotine products;Levy;Addiction,2017

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