A highly sensitive and rapid LC-MS/MS method for quantification of bexarotene in mouse plasma and brain tissue: Application to mice pharmacokinetic study

Author:

Fu Huimei,Chu Lijuan,Jiao He,Lin Longyi,Liu Youping,Chen Guoliang,Zou Libo,Wang Xin,Di Xin

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference15 articles.

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4. Bexarotene promotes cholesterol efflux and restricts apical-to-basolateral transport of amyloid-β peptides in an in vitro model of the human blood-brain barrier;Kuntz;J. Alzheimers Dis.,2015

5. J. Habchi1, P. Arosio1, M. Perni1, A.R. Costa1, M. Yagi-Utsumi1, P. Joshi1, S. Chia1, S.I. Cohen, M.B. Müller, S. Linse, E.A. Nollen, C.M. Dobson, T.P. Knowles1, M. Vendruscolo1, 2016. An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease. Sci. Adv. 2, e1501244. https://advances.sciencemag.org/content/2/2/e1501244.

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