A HILIC-UHPLC–MS/MS untargeted urinary metabonomics combined with quantitative analysis of five polar biomarkers on osteoporosis rats after oral administration of Gushudan

Author:

Wu Xiao,Huang Yue,Sun Jinghan,Wen Yongqing,Qin Feng,Zhao Longshan,Xiong Zhili

Funder

National Natural Science Foundation of China

Outstanding Young Scholar Growth Plan in Liaoning Province, China

The Young and Middle-aged Teachers Development Support Plan of Shenyang Pharmaceutical University

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference41 articles.

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3. The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans;Dunn;Bioanalysis,2012

4. Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics;Hirata;Clin. Chim. Acta,2017

5. Metabolomics studies in brain tissue: a review;Gonzalezriano;J. Pharm. Biomed. Anal.,2016

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