Validated extended multiplexed LC-MS/MS assay for the quantification of adagrasib and sotorasib in human plasma, together with four additional SMIs

Author:

Kruithof Paul D.ORCID,de Beer Yvo M.,Gulikers Judith L.,Stolk Leo M.L.,Hendriks Lizza E.L.,Croes Sander,van Geel Robin M.J.M.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference19 articles.

1. Personalized therapy for lung cancer: striking a moving target;Pakkala;JCI Insight,2018

2. Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRAS(G12C) mutation: a randomised, open-label, phase 3 trial;de Langen;Lancet,2023

3. Long-term outcomes and molecular correlates of sotorasib efficacy in patients with pretreated KRAS G12C-mutated non-small-cell lung cancer: 2-year analysis of codebreak 100;Dy;J. Clin. Oncol.,2023

4. T.S. Bekaii-Saab, R. Yaeger, A.I. Spira, M.S. Pelster, J.K. Sabari, N. Hafez, M. Barve, K. Velastegui, X. Yan, A. Shetty, H. Der-Torossian, S. Pant, Adagrasib in advanced solid tumors harboring a KRAS(G12C) mutation, J. Clin. Oncol. doi: 10.1200/jco.23.00434(2023) Jco2300434.

5. Adagrasib in non-small-cell lung cancer harboring a KRAS(G12C) mutation;Jänne;N. Engl. J. Med.,2022

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