Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping-Reference-Cited by-同舟云学术

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Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping

Published:2024-01 Issue: Volume:1232 Page:123962
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Abouir Kenza^ORCID,Samer Caroline,Landry Romain,Varesio Emmanuel,Daali Youssef

Funder

Swiss National Science Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference28 articles.

1. Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors;Shin;J. Am. Chem. Soc.,2004

2. Corp RD. Drug Label Information Updated January 12, 2011. (Accessed 04 December 2023).

3. Stereoselective metabolism of omeprazole by cytochrome P450 2C19 and 3A4: mechanistic insights from DFT study;Jana;J. Phys. Chem. B.,2018

4. Effects of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of proton pump inhibitors;Zhang;Pharmacol. Res.,2020

5. Safety of the geneva cocktail, a cytochrome P450 and P-glycoprotein phenotyping cocktail, in healthy volunteers from three different geographic origins;Rollason;Drug Saf.,2020

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